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Research interestsOur lab is focused on the study of normal and abnormal lung and lung vascular development as related to pulmonary endothelial nitric oxide synthase (eNOS) and its regulation of pulmonary vascular tone. In addition, we are studying novel approaches to the treatment of pulmonary hypertension utilizing gene therapeutic approaches. Several ongoing studies using models ranging from cell culture to isolated lung to whole animals, and techniques ranging from RNA interference to physiological studies are directed at answering questions relating to eNOS expression and NO production, and their effect on pulmonary artery tone during development.Contact info
Address: The Ohio State University WA3021 Children's Research Institute Columbus, Oh 43205 Phone: 614-722-2683 Email: Chicoin1@ccri.net
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