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Research interestsResearch area: The Bohn lab asks how opiate narcotics, such as morphine, methadone and heroin, mediate physiological effects such as pain relief, tolerance, dependence and addiction. Morphine activates the mu opioids receptor which is a member of the G protein-coupled receptor (GPCR) family and is subject to cellular regulation, an event that can determine the potency of the drug. Utilizing signal transduction assays in cell cultures combined with behavioral and physiological testing in genetically modified mice, we study the contribution of receptor regulation to the overall effect of opiates.Contact info
Address: The Ohio State University Dept. of Pharmacology Columbus, Oh 43210 Phone: 614-292-1303 Email: bohn.24@osu.edu
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