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John Barnard

John Barnard

Research interests

Research Area: The Barnard laboratory is interested in the cell biology of intestinal epithelial proliferation and how intestinal cells become resistant to inhibition by transforming growth factor (TGF) beta. Using cell culture models of Ras-transformation, they are determining the precise points in TGF beta signaling that are disrupted by oncogenic Ras. In addition, interactions between the Ras pathway and the Rho signaling pathway are being examined. Dr. Barnard?s studies are relevant to the biology of colorectal cancers, 90% of which are resistant to growth inhibition by TGF-beta.

Contact info

Address:
The Ohio State University
Children's Research Institute
Columbus, Oh 43210
Phone: (614) 722-2735
Email: barnardj@pediatrics.ohio-state.edu

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Integrated Biomedical Science Graduate Program
Room 1190 Graves Hall, 333 West 10th Avenue
Columbus, Ohio 43210
Telephone: 614-292-0857
FAX: 614-292-6226
info@ibgp.org

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