Integrated Biomedical Science Graduate Program at The Ohio State University

Research interests

Research Area: The research in Dr. Bartlett?s laboratory focuses on the development of viral vectors for human gene therapy. Most of their work involves adeno-associated virus (AAV) vectors, although they also work with adenovirus vectors and molecular targeted viral conjugates. The laboratory has active and funded research programs in cystic fibrosis gene therapy, and in gene therapies for the treatment of brain and ovarian cancers. A main interest of the laboratory has been to define the endogenous tropism of viral vectors as a basis for subsequent modifications to alter host cell range. Research has focused on the development of targetable vector systems and the biodistribution and sub cellular fate of gene therapy vectors in vivo. This work has led to the development of novel technologies for the cell-specific delivery of gene-medicines and the pharmacological analysis of virus-mediated gene therapies.

Contact info

Address:
Gene Therapy Center
Children's Research Institute
Columbus, Oh 43205
Phone: (614) 722-2876
Email: BartletJ@pediatrics.ohio-state.edu

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Jeffrey Bartlett

Research interests

Contact info