The Ohio State University Integrated Biomedical Science Graduate Program; Room 1190 Graves Hall, 333 West 10th Avenue Columbus, Ohio 43210 Telephone: 614:292-0857 Fax: 614-292-6226 IBGP

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Howard Gu

Howard Gu

Research interests

Research area: Currently there are three research projects: (1) we are in the process of making a knock-in mouse model carrying a cocaine resistant functional dopamine transporter (DAT) to study the role of DAT in cocaine addiction; (2) in collaboration with the scientists and clinicians in the department of Psychiatry, we are screening patients with mental disorders for single nucleotide polymorphisms (SNPs) in critical genes to uncover the genetic basis of certain mental disorders; (3) we have engineered a functional DAT construct with all reactive cysteine residues removed which allow us to study the 3-D structure of DAT, where cocaine binds, and potentially what new drugs can be developed to treat cocaine addiction.

Contact info

Address:
The Ohio State University
Dept. of Pharmacology
Columbus, Oh 43210
Phone: 614-292-1324
Email: gu.37@osu.edu
 
 


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Integrated Biomedical Science Graduate Program
Room 1190 Graves Hall, 333 West 10th Avenue
Columbus, Ohio 43210
Telephone: 614-292-0857
FAX: 614-292-6226
info@ibgp.org

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