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Carl Bates

Carl Bates

Research interests

Dr. Bates is an Investigator, Center for Cell and Developmental Biology, Columbus Children?s Research Institute and Assistant Professor of Pediatrics, Division of Nephrology, Department of Pediatrics, College of Medicine, The Ohio State University. The focus of Dr. Bates? research is on genes critical for kidney development. In particular, the main genes of interest are the fibroblast growth factor receptors (FGFRs). Using a conditional knockout approach in mice, the laboratory has discovered that FGFRs in the metanephric mesenchyme are critical for early kidney patterning events in both the mesenchyme and ureteric bud. FGFR2 in the ureteric bud is necessary for proper patterning of the ureteric bud tree and the stromal mesenchyme. In addition, loss of FGFR2 in the ureteric bud leads to a decrease in nephron number in utero which is associated with hypertension and renal failure in adult mice.

Contact info

Address:
The Ohio State University
Dept. of Pediatrics
Columbus, Oh 43205
Phone: 614-355-2818
Email: batesc@pediatrics.ohio-state.edu
 
 


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Integrated Biomedical Science Graduate Program
Room 1190 Graves Hall, 333 West 10th Avenue
Columbus, Ohio 43210
Telephone: 614-292-0857
FAX: 614-292-6226
info@ibgp.org

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